Tuesday, September 01, 2009
Traumatic Hemorrhagic Shock - An Update
1. Kwan, I., Bunn, F. & Roberts, I. (2003). Timing and volume of fluid administration for patients with bleeding. Cochrane Database Syst Rev, (3), CD002245.
This Cochrane review shows that to date, there is a lack of uniformity in terms of study designs and patients population. Data pooling could not be performed. At the current moment, it is inconclusive to give a strong recommendation to permissive hypotension.
2. Turner, J., Nicholl, J., Webber, L., Cox, H., Dixon, S. & Yates, D. (2000). A randomised controlled trial of prehospital intravenous fluid replacement therapy in serious trauma. Health Technol Assess, 4 (31), 1-57.
This is one of the larger study done to look into early versus delayed fluid resuscitation in trauma, as compared to the study by Bickell et al. The methodology is very well described in the full text of the monograph.
3. Spahn, D. R., Cerny, V., Coats, T. J., Duranteau, J., Fernandez-Mondejar, E., Gordini, G., Stahel, P. F., Hunt, B. J., Komadina, R., Neugebauer, E., Ozier, Y., Riddez, L., Schultz, A., Vincent, J. L. & Rossaint, R. (2007). Management of bleeding following major trauma: a European guideline. Crit Care, 11 (1), R17.
This is a comprehensive European guideline on traumatic hemorrhage
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